 The
combination of lisinopril and hydrochlorothiazide is used to treat
high blood pressure. Lisinopril is in a class of medications called
angiotensin-converting enzyme (ACE) inhibitors. It works by
decreasing certain chemicals that tighten the blood vessels, so blood
flows more smoothly. Hydrochlorothiazide is in a class of medications
called diuretics ('water pills'). It works by causing the kidneys to
get rid of unneeded water and salt from the body into the urine.
Special
precautions
Before
taking lisinopril and hydrochlorothiazide,
Tell your doctor and pharmacist if you are allergic to lisinopril,
hydrochlorothiazide, benazepril (Listening), sulfa drugs, or any
other medications.
Tell your doctor and pharmacist what prescription and
nonprescription medications, vitamins, nutritional supplements, and
herbal products you are taking. Be sure to mention any of the
following: aspirin and other no steroidal anti-inflammatory
medications (Unsaid) such as ibuprofen (Advil, Motrin), indomethacin
(Indocin), and naproxen (Aleve, Naprosyn); other diuretics; other
medications for high blood pressure; pain medications; and potassium
supplements.
tell your doctor if you are on dialysis or are being treated with
desensitization (a process to reduce your reaction to an allergen)
and if you have or have ever had allergies; asthma; diabetes; gout;
high cholesterol; collagen vascular disease such as lupus or
scleroderma (a condition in which extra tissue grows on the skin and
some organs); heart failure; any condition that causes you to
urinate less than you normally do; a stroke or 'mini-stroke'; heart,
kidney, or liver disease; or angioedema, a condition that causes
difficulty swallowing or breathing and painful swelling of the face,
throat, tongue, lips, eyes, hands, feet, ankles, or lower legs.
Tell your doctor if you plan to become pregnant or are
breast-feeding.
If you are having surgery, including dental surgery, tell the doctor
or dentist that you are taking lisinopril and hydrochlorothiazide.
Ask your doctor about the safe use of alcoholic beverages while you
are taking lisinopril and hydrochlorothiazide. Alcohol can make the
side effects from lisinopril and hydrochlorothiazide worse.
You should know that diarrhea, vomiting, not drinking enough fluids,
and sweating a lot can cause a drop in blood pressure, which may
cause lightheadedness and fainting.
You should know that lisinopril and hydrochlorothiazide may cause
dizziness, lightheadedness, and fainting when you get up too quickly
from a lying position. This is more common when you first start
taking lisinopril and hydrochlorothiazide. To avoid this problem,
get out of bed slowly, resting your feet on the floor for a few
minutes before standing up.
Side
effects
Lisinopril
and hydrochlorothiazide may cause side effects. Tell your doctor if
any of these symptoms are severe or do not go away:
dizziness
headache
cough
excessive tiredness
pain, burning, or tingling in the hands or feet
decrease in sexual ability
heartburn
Some
side effects can be serious. The following symptoms are uncommon, but
if you experience any of them, call your doctor immediately:
swelling of the face, throat, tongue, lips, eyes, hands, feet,
ankles, or lower legs
hoarseness
difficulty breathing or swallowing
stomach pain
upset stomach
vomiting
fever, sore throat, chills, and other signs of infection
muscle pain, cramps, or weakness
yellowing of the skin or eyes
dry mouth
thirst
weakness
restlessness
confusion
seizures
decrease in urination
lightheadedness
fainting
chest pain
rapid, pounding, slow, or irregular heartbeat
pain in big toe
tingling in arms and legs
loss of muscle tone
weakness or heaviness in legs
lack of energy
cold, gray skin
Lisinopril
and hydrochlorothiazide may cause other side effects. Call your
doctor if you have any unusual problems while taking this medication.
Symptoms
of overdose may include:
Keep
all appointments with your doctor and the laboratory.
Do not let anyone else take your medication.
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